Question

vicissitude 【vicissitude】n.变迁；变化The future is so uncertain that we cannot know all the vicissitudes of our fortunes.未来是无法确知的，我们无法知道将来的命运所有的变化。

Accepted Answer

[vɪ'sɪsɪtuːd] 
vicissitudea variation in circumstances or fortune at different times in your life or in the development of something
When you talk of the vicissitudes of life, you're referring to the difficult times that we all go through: sickness, job loss, and other unwelcome episodes. No one can escape the vicissitudes of life.
While vicissitude comes from the Latin vicis, which means "change" and technically can mean a change of any kind, you'll find that vicissitude is almost always used to talk about an unfortunate event or circumstance. Losing a pet, crashing the car, being called in for jury duty: these are examples of vicissitudes — chapters in one's life that one would rather avoid but must get through. Some lives have more vicissitudes than others, to be sure, but no life is without events that test and challenge us.
All forms of 'vicissitude' will appear on average once every 1700 pages.vicissitude

Front	vicissitude
Pron	[vɪ'sɪsɪtuːd]
Back	【vicissitude】 n.变迁；变化 The future is so uncertain that we cannot know all the vicissitudes of our fortunes. 未来是无法确知的，我们无法知道将来的命运所有的变化。
Vocab	vicissitudea variation in circumstances or fortune at different times in your life or in the development of something When you talk of the vicissitudes of life, you're referring to the difficult times that we all go through: sickness, job loss, and other unwelcome episodes. No one can escape the vicissitudes of life. While vicissitude comes from the Latin vicis, which means "change" and technically can mean a change of any kind, you'll find that vicissitude is almost always used to talk about an unfortunate event or circumstance. Losing a pet, crashing the car, being called in for jury duty: these are examples of vicissitudes — chapters in one's life that one would rather avoid but must get through. Some lives have more vicissitudes than others, to be sure, but no life is without events that test and challenge us. All forms of 'vicissitude' will appear on average once every 1700 pages. vicissitude

Vicissitudes Life Times Talk Vɪ'Sɪsɪtuːd N.变迁；变化 Future Uncertain