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Merriam-Webster's Collegiate Dictionary an·tag·o·nist DATE 1575 1. one that contends with or opposes another : adversary , opponent 2. an agent of physiological antagonism: as a. a muscle that contracts with and limits the action of an agonist with which it is paired — called also antagonistic muscle b. a chemical that acts within the body to reduce the physiological activity of another chemical substance (as an opiate); especially :one that opposes the action on the nervous system of a drug or a substance occurring naturally in the body by combining with and blocking its nervous receptor — compare agonist 2bEnglish Etymology antagonist c.1600, from L. antagonista, from Gk. antagonistes "competitor, opponent, rival," from antagonizesthai "to struggle against," from anti- "against" + agonizesthai "to contend for a prize," from agon"contest" (see agony). Originally in battle or sport, extended 1620s to any sphere of human activity. Related: Antagonistic (1630s). Oxford Advanced Learner's Dictionary-牛津双解-OALD7 antagonist an·tag·on·ist / An5tA^Enist / noun (formal)a person who strongly opposes sb / sth 对立者;对抗者;对手;敌人 SYN opponent
Webster's Third New International Dictionary, Unabridged Search result show the entry is found in: H2 antagonist , or H2 receptor antagonist an·tag·o·nist \-_nə̇st\ noun (-s) Etymology: Late Latin antagonista, from Greek antagōnistēs, from antagōnizesthai 1. a. : one that contends with or opposes another (as in a fight, conflict, or other contest) : opponent , adversary < completely vanquishing his antagonist > b. : the principal opponent or foil of the main character in a drama or narrative < the crook was the antagonist to the detective hero > — opposed to protagonist 2. : an agent that acts in physiological opposition < contact between a tooth and its antagonist in the opposing jaw > as a. : a muscle that contracts with and limits the action of an agonist with which it is paired b. : a drug that opposes the action on the organism of another drug by a physiological, chemical, or competitive mechanism |
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