Gradually Immunity Poison Taking Doses Vi's Tolerance Mithridatism

mithridatism /MITH-ri-day-tiz-uhm/

noun

The developing of immunity to a poison by taking gradually increasing doses of it.

[After Mithridates VI, king of Pontus (now in Turkey) 120-63 BCE, who is said to have acquired immunity to poison by ingesting gradually larger doses of it. Earliest documented use: 1851. Mithridates VI's father was poisoned. No wonder VI wanted to develop tolerance to poison. The story goes that after VI's defeat by Pompey, he didn't want to be captured alive. So he tried to end his life by taking poison. That didn't work, so he had a servant stab him with a sword.]

"Some monks resorted to the direct ingestion of mercury and cinnabar, small quantities at first, but gradually building up the dosage as the body's tolerance increased -- an alchemical mithridatism." Alexander Goldstein; The Foundling; Trafford Publishing; 2009.