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End Hope Informal Guardian Underlying Problem Science Fact

Word Be all up with = It is all up with
Description It is the end or there is no hope for someone or something - Informal

2002 - Guardian - The underlying problem is not the science itself, but the fact that the science is telling politicians something they are desperate not to hear….that it's all up with our current model of gung-ho globalisation. It is the end or there is no hope for someone or something - Informal

2002 - Guardian - The underlying problem is

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