Front | What is cancer, what are the two types of genes that control the cell cycle and does the p53 protein do |
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Back | The abnormal, uncontrollable growth of cells (a tumour is the mass of cells with mutant DNA) - in each cells cycle it is very unlikely to get the exact combination of mutations to do this but there are so many cells in the body so this makes it possible Oncogenes cause a cell to transition from one stage of the cell cycle to the next; tumour suppressor genes stop the cell cycle (mutations in these genes can cause cancer) P53 is a tumour suppressor gene that repairs the DNA to fix mutations, disrupts the cell cycle or causes cell suicide to prevent a tumour growing in response to cellular stress (DNA damage or activated oncogenes) |
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