Question

Antifungal therapyAmphotericin B3 general symptoms2 specific organ toxicities, and what decreases this?2 heme toxicitiesWhat form of this drug is less toxic?

Accepted Answer

Fever/chills (“shake and bake”), hypotension

nephrotoxicity, (Hydration decreases nephrotoxicity)

arrhythmias,

anemia

IV phlebitis (“amphoterrible”).

Liposomal amphotericin has less toxicity.

Front	Antifungal therapy Amphotericin B 3 general symptoms 2 specific organ toxicities, and what decreases this? 2 heme toxicities What form of this drug is less toxic?
Back	Fever/chills (“shake and bake”), hypotension nephrotoxicity, (Hydration decreases nephrotoxicity) arrhythmias, anemia IV phlebitis (“amphoterrible”). Liposomal amphotericin has less toxicity.

Amphotericin Antifungal Therapy B General Symptoms Specific Organ