This flashcard details Streptococcus pyogenes (group A strep), its superantigen (streptococcal pyrogenic exotoxin A, SpeA) binding to T cell receptors and MHC II, causing massive cytokine release, leading to streptococcal toxic shock.
Cette flashcard détaille le Streptococcus pyogenes (streptocoque du groupe A), son superantigène (streptocoque pyrogène exotoxine A, SpeA) qui se lie aux récepteurs des cellules T et du CMH II, provoquant une libération massive de cytokines, conduisant au choc toxique lié aux streptocoques.
| Front | Bugs with exotoxins: Superantigens causing shock: Streptococcus pyogenes toxin: 1 mechanism: binds to?2 where? causes?4 --> ?? Manifestation: 1 syndrome - 3 symptoms |
|---|---|
| Back | same mechanism as TSST-1 |
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