This graph illustrates the course of untreated HIV infection, showing high viral load and declining CD4+ cells in the acute phase, viral replication in lymph nodes during latency, and a resurgence of viral load with severe CD4+ depletion (<200 cells/mm³) in the AIDS phase, indicating moderate (<400) and severe (<200) immunosuppression.
該圖顯示了HIV感染的時間進程：急性期病毒載量急劇升高，CD4+細胞計數下降；潛伏期病毒複製，CD4+細胞緩慢下降；AIDS期CD4+細胞計數極低，病毒載量再次升高。嚴重的免疫抑制（<400 CD4+細胞/mm³）和愛滋病定義性疾病（<200 CD4+細胞/mm³）會出現。
| Front | Time course of untreated HIV infection what is going on in acute phase? |
|---|---|
| Back | Red line = CD4+ T cell count (cells/mm3); blue line = HIV RNA copies/mL Blue boxes on vertical CD4+ count axis indicate moderate immunocompromise (< 400 CD4+ cells/mm3) and when AIDS-defining illnesses emerge (< 200 CD4+ cells/mm3). plasma. |
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