All paramyxoviruses contain the surface F (fusion) protein, which causes respiratory epithelial cells to fuse and form multinucleated cells. Palivizumab, a monoclonal antibody against the F protein, can prevent RSV-induced pneumonia in premature infants.
副黏液病毒科病毒均含有表面F(融合)蛋白,該蛋白可使呼吸道上皮細胞融合形成多核細胞。帕利珠單抗(一種針對F蛋白的單株抗體)可用於預防早產兒因RSV感染引起的肺炎。
Front | Paramyxoviruses All contain what protein? What does this protein cause/form? What drug can DO WHAT? for what disease (from which virus, in what population)? |
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Back | All contain surface F (fusion) protein, which causes respiratory epithelial cells to fuse and form multinucleated cells. Palivizumab (monoclonal antibody against F protein) prevents pneumonia caused by RSV infection in premature infants. |
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