This flashcard describes the mechanism of action of NRTIs, which competitively inhibit nucleotide binding to reverse transcriptase and terminate the DNA chain.
Cette flashcard décrit le mécanisme d'action des NRTI, qui inhibent de manière compétitive la liaison des nucléotides à la transcriptase inverse et terminent la chaîne d'ADN.
| Front | HIV therapy NRTIs MOA: 2 |
|---|---|
| Back | Competitively inhibit nucleotide binding to reverse transcriptase and terminate the DNA chain (lack a 3′ OH group). |
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