This flashcard lists adverse effects of isoniazid, including hepatotoxicity (CYP450 inhibition), and vitamin B6 problems (neuropathy, anemia) treatable with supplements. It also mentions the importance of slow/fast metabolizer status.
Cette flashcard liste les effets indésirables de l'isoniazide, y compris l'hépatotoxicité (inhibition de la CYP450), et les problèmes de vitamine B6 (neuropathie, anémie) qui peuvent être traités avec des suppléments. Elle mentionne également l'importance du statut de métaboliseur lent/rapide.
| Front | Isoniazid Adverse: toxic to what? what enzyme is inhibited or activated? What special adverse? What vitamin problem, with 2 symptoms? how to treat this? What population/genetic effect do you have to worry about as far as the efficacy/toxicity of this drug is concerned? |
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