HBV DNA polymerase possesses both DNA- and RNA-dependent activities. Upon entering the host cell nucleus, it completes viral DNA replication. Host RNA polymerase then transcribes viral DNA into mRNA for viral protein synthesis, and the viral DNA polymerase reverse transcribes viral RNA into DNA, forming the genome of progeny viruses.
B型肝炎病毒的DNA聚合酶同時具有DNA和RNA依賴性活性。進入宿主細胞核後，DNA聚合酶會完成病毒DNA的複製。接著，宿主細胞的RNA聚合酶會將病毒DNA轉錄為mRNA，用於合成病毒蛋白。最後，DNA聚合酶會將病毒RNA逆轉錄為DNA，形成子代病毒的基因組。
| Front | Hepatitis viruses HBV carries what with it? it has 2 activities Upon entry into ________, this protein does what? What does the host machinery do with this? The viral protein then does what with this?[this is creating?] |
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| Back | HBV DNA polymerase has DNA- and RNA-dependent activities. Upon entry into nucleus, the polymerase completes the partial dsDNA. Host RNA polymerase transcribes mRNA from viral DNA to make viral proteins. The DNA polymerase then reverse transcribes viral RNA to DNA, which is the genome of the progeny virus. |
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