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Activated Flucytosine Fungal Cells Converted Enzyme Inhibit Cytosine

Front How is flucytosine activated in fungal cells?

What is it converted into?

What enzyme does it inhibit?
Back

Activated by cytosine deaminase into 5-FU which inhibits thymidylate synthase preventing conversion of dUMP→dTMP


Tags: antifungal, drugs

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