Aminoglycosides inhibit initiation complex formation by binding to the 30S ribosomal subunit, causing mRNA misreading, and are used to treat aerobic gram-negative rods.
Aminoglykosidit estävät initiaatiokompleksin muodostumista sitoutumalla 30S-ribosomiyksikköön ja aiheuttavat mRNA:n virheenlukua; niitä käytetään aerobisten gram-negatiivisten sauvojen hoitoon.
| Front | Aminoglycosides → MOA → use |
|---|---|
| Back | Inhibit formation of initiation complex by binding to 30S ribosomal subunit and causing misreading of mRNA → treat aerobic gram (-) rods |
Tags: antimicrobial, drugs
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