The combination of flucytosine and amphotericin B is used for cryptococcal meningitis, where amphotericin B increases membrane permeability to flucytosine, creating a synergistic effect.
Kombinacija flucitozina i amfotericina B koristi se za lečenje kriptokoknog meningitisa, gde amfotericin B povećava propustljivost membrane za flucitozin, pružajući sinergijski efekat.
| Front | Combination flucytosine | amphotericin B → use |
|---|---|
| Back | Cryptococcal meningitis ↓ Amphotericin B ↑membrane permeability to flucytosine → both drugs are synergistic in effect |
Tags: antifungal, drugs
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