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Botulism Toxin Describe Pathogenesis Infant Ingestion C.Botulinum Endospores

Infant botulism results from ingested C. botulinum spores germinating and producing toxin in the infant gut; adult botulism involves ingesting preformed toxin.

Infant botulism occurs when C. botulinum spores are ingested from the environment (like honey), germinate in the infant's immature gut, and produce toxin in vivo. In adult botulism, preformed toxin is ingested.

Front Describe pathogenesis of Infant Botulism
Back
Ingestion of C.botulinum endospores from the environment (honey) → spores germinate in the alkaline pH of immature GIT → toxin produced in vivo → in adult botulism, the preformed toxin is ingested

Tags: microbiology

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