This flashcard describes Bendazoles (Albendazole, Mebendazole) as microtubule inhibitors that disrupt cell division, motility, and intracellular transport, and impair glucose uptake.
This flashcard describes Bendazoles (Albendazole, Mebendazole) as microtubule inhibitors that disrupt cell division, motility, and intracellular transport, and impair glucose uptake.
| Front | Bendazoles→ MOA → (2) drugs |
|---|---|
| Back | Microtubule inhibitors Binds colchicine-sensitive site of β-tubulin and inhibit microtubule assembly Impaired uptake of glucose (↓ glycogen stores) Prevents spindle fibers formation needed for cell division Cell motility, maintenance of cell shape, and intracellular transport are also disrupted Albendazole Mebendazole |
Tags: antiparasitic, drugs
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