Clindamycin is effective against anaerobic infections above the diaphragm and acts on the 50S subunit. Metronidazole is effective against anaerobic infections below the diaphragm and damages bacterial DNA via free radicals.
Klindamicin je efikasan protiv anaerobnih infekcija iznad dijafragme i deluje na 50S podjedinicu. Metronidazol je efikasan protiv anaerobnih infekcija ispod dijafragme i oštećuje bakterijski DNK putem slobodnih radikala.
| Text | Clindamycin::drug → effective in treating anaerobic infx above diaphragm Metronidazole::drug → effective in treating anaerobic infx below diaphragm |
|---|---|
| Extra | Clindamycin works on 50S subunit to stop protein synthesis Metronidazole makes free radicals which damage bacterial DNA |
Tags: antimicrobial, drugs
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