| Front | What organism causes Cold Agglutinin Disease and leads to AIHA? |
|---|---|
| Back | M.pneumonia ↓ Gram variable with NO cell wall and cholesterol in cell membrane ↓ Result in Cold Agglutinin Disease 2˚ to IgM production ↓ Cold Agglutinin Disease and Warm Autoimmune Hemolytic Anemia (AIHA) show antibodies directed against host cells with complement activation that induces hemolysis and causes anemia ↓ (+) direct antiglobulin (Coombs) test ↓ Cold agglutinin disease (autoimmune hemolytic anemia caused by M.pneumoniae) results in antibodies that agglutinate in cold temperatures |
Tags: microbiology
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