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Conjunctivitis C.Trachomatis Image Presents Days Birth Neonatal Inclusion

Front List (2) diseases C.trachomatis cause in newborns

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Conjunctivitis presents 5 -14 days after birth with inflammation | swollen eyelids | yellow purulent dischargeN.gonorrhoeae is another common cause of neonatal conjunctivitis but it present 2-5 days after birth

Pneumonia presents at 4-11 weeks of life with cough | respiratory distress; CBC shows eosinophilia (commonly tested point on the Step 1 exam)

Image above shows eukaryotic cells infected with C.trachomatis, in which the diffuse inclusion body in the center of the cell pushes the nucleus to the cell's periphery. All neonates born in the U.S. are given prophylactic erythromycin eye drops to decrease the risk of gonococcal conjunctivitis, but this practice does not effectively prevent chlamydial conjunctivitis. Aggressive therapy with topical and oral erythromycin is warranted in neonates with inclusion conjunctivitis, both to treat the conjunctivitis and to prevent the development of neonatal pneumonia as a result of descending infectio which spreads from the eyes, nasopharynx (via nasolacrimal duct), downwards towards the lungs. 

Tags: microbiology

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