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Difficulty Food Neurotoxin Botulism Symptoms Pathogenesis Diplopia Double

Front Botulism 



What are Symptoms?
What is the Pathogenesis?
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Diplopia (double vision)
Dyspnea (difficulty breating)
Dysphagia (difficulty swallowing)
Dysphonia (difficulty talking)

Anerobic environment in canned food contaminated by C.botulinum 
↓ 
Spores germinate and organism grows
↓ 
C.botulinum neurotoxin remains intracellular
Autolysis releases neurotoxin into food
↓ 
If food containing the pre-formed neurotoxin is not cooked well, the neurotoxin will exert its effects 
↓ 
Toxin is not actively secreted by the bacteria and is readily destroyed by heating 

Tags: microbiology

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