Linezolid blocks the 50S subunit to prevent initiation complex formation, resistance arises from point mutation, and adverse effects include bone marrow suppression and serotonin syndrome; it is used for Gram-positive organisms, including MRSA and VRE.
Linezolid blokira 50S podjedinicu za formiranje inicijalnog kompleksa, rezistencija nastaje tačkastom mutacijom, a neželjeni efekti uključuju supresiju koštane srži i serotonin sindrom. Koristi se za Gram-pozitivne organizme, uključujući MRSA i VRE.
| Front | What drug is being described below? What is its main clinical use? Blocks 50S subunit to prevent initiation complex formation Resistance by point mutation A/E include bone marrow suppression and Serotonin Syndrome |
|---|---|
| Back | Linezolid Gram (+) bugs MRSA VRE |
Tags: antimicrobial, drugs
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