| Front | (3) NNRTIs → mechanism of action |
|---|---|
| Back | Delavirdine Efavirenz Nevirapine Inhibit enzyme (reverse transcriptase) on sites different from NRTIs → original genetic information from HIV is in form of RNA and enzyme is needed to convert ssRNA to dsDNA → two classes of reverse transcriptase inhibitors → Non-Nucleoside Reverse Transcriptase Inhibitors (nevirapine) bind enzyme directly to block catalytic site → Nucleoside Reverse Transcriptase Inhibitors (zidovudine) are incorporated into DNA strand to prevent elongation |
Tags: antiviral, drugs
Learn with these flashcards. Click next, previous, or up to navigate to more flashcards for this subject.
Next card: Nnrtis are contraindicated pregnancy delavirdine efavirenz
Previous card: Nrti contraindicated patient hla-b5701 mutation due risk hypersensitivity
Up to card list: Microbiology 101 → Step 1 USMLE