ETEC LT activates adenylate cyclase increasing cAMP, leading to chloride and water secretion into the gut, while ETEC ST activates guanylate cyclase increasing cGMP, reducing NaCl and water reabsorption.
ETEC LT, adenilat siklazı aktive ederek cAMP'yi, ETEC ST ise guanilat siklazı aktive ederek cGMP'yi artırır; bu da sırasıyla bağırsaklara klorür ve su salınımına veya NaCl ve su geri emiliminin azalmasına yol açar.
| Front | ETEC Heat LT vs. ETEC Heat ST |
|---|---|
| Back | ETEC LT Activates adenylate cyclase→ ↑cAMP ↑Cl- | H2O secretion into gut ETEC ST Activates guanylate cyclase→ ↑cGMP ↓NaCl | H2O reabsorption out of gut |
Tags: microbiology
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