Cephalosporins are divided into 5 generations; the first two have a narrow spectrum, while the last three are broad-spectrum, all acting by inhibiting transpeptidases and peptidoglycan cross-linking.
There are 5 generations of Cephalosporins, with the first two having a narrow spectrum and the latter three having a broad spectrum. They work by blocking transpeptidases and reducing peptidoglycan cross-linking.
| Front | How many Cephalosporins generations → MOADS |
|---|---|
| Back | 1st 2nd generation ↓ Narrow spectrum 3rd 4th 5th generation ↓ Broad spectrum Mechanism of action ↓ Block transpeptidases and ↓peptidoglycan crosslinking in bacterial cell wall |
Tags: antimicrobial, drugs
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