Strongyloides infection and superinfection occur as filariform larvae penetrate the skin, migrate through lungs and gut, mature, and spread via fecal-oral or re-infection routes, with immunosuppressed individuals at high risk for hyperinfection.
Strongyloides-hypertartunta ja superinfektio johtuu siitä, että filariform-toukat tunkeutuvat ihoon, leviävät keuhkoihin ja suolistoon, lisääntyvät ja leviävät edelleen hyttysillä sekä reinfektoivat tai tartuttavat muita.
| Front | What is the mechanism behind Strongyloides infection and superinfection? |
|---|---|
| Back | Filariform larvae enter skin via soil contaminated with human feces ↓ Larvae migrates through blood to the lungs ↓ Larve ascend from the lungs into GIT ↓ Larvae mature in GIT to adulthood to lay eggs ↓ Rhabditiform larvae hatch from eggs and mature into filariform larvae which are excreted in the stool ↓ Filariform larvae leave via the anus and infect others or reinfect the patient by penetrating the perianal skin ↓ Result in a large burden of disease called hyperinfection ↓ Immunosuppressed individuals are at high risk hyperinfection ↓ Patients with strongyloidiasis will be found to have asymptomatic eosinophilia |
Tags: microbiology
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