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Microbiology 101 → Step 1 USMLE

Lipopolysaccharide Define Cite Components Endotoxin Located Outer Membrane

Lipopolysaccharide (LPS), an endotoxin in Gram-negative bacteria, consists of core polysaccharide, O antigen, and toxic lipid A, triggering inflammatory responses that can cause septic shock.

Lipopolysaccharide (LPS) is an endotoxin in the outer membrane of gram-negative bacteria, composed of core polysaccharide, O antigen, and toxic lipid A. It triggers macrophage, complement, and tissue factor activation, potentially leading to septic shock.

Front Lipopolysaccharide - define and cite (3) components
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Endotoxin located in the outer membrane of gram-negative bacteria. Composed of a core polysaccharide, O antigen (immunogenic component), and lipid A (toxic component). Triggers macrophage, complement, and tissue factor activations. Associated with septic shock.

Tags: microbiology

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