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Mri Demyelination White Matter Jc Virus Neuronal Cells

Front What does JC virus cause?

What neuronal cells does it affect?

What are clincial manifestations?

What are MRi findings?

What is the treatment?
Back

Progressive Multifocal Leukoencephalopathy in immunocompromised AIDS patients

Oligodendrocyte demyelination

Manifestations
↓ 
Headache
Speech Issues
Altered mental status (AMS)
Hemiparesis | Limb ataxia
Visual symptoms (hemianopia)

MRI Findings
Demyelination in white matter of CNS 
(arrows in image)

FLAIR MRI demonstrates subcortical white matter signal T2 weighted hyperintensity





Treatment
Highly Active Antiretroviral Therapy (HAART)

Tags: microbiology

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