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Pathogenesis Described?  Filovirus  Which Infects Endothelial Cells|Phagocytes|Hepatocytes  Release

This flashcard describes the pathogenesis of Ebola virus, a filovirus that infects various cells, releases inflammatory cytokines, and causes severe symptoms like hemorrhage, DIC, and shock.

Filovirus, which infects endothelial cells, phagocytes, and hepatocytes, causes the release of TNF-α, IL-6, and IL-8, leading to flu-like symptoms, diffuse hemorrhage, DIC, and shock. This describes the pathogenesis of Ebola virus.

Front What pathogenesis is being described? 
What is the cause?

Filovirus which infects endothelial cells|phagocytes|hepatocytes 
Causes release of TNF-α | IL-6 | IL-8
Flu-like symptoms | Diffuse hemorrhage | DIC | Shock
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Ebola virus




Tags: microbiology

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