| Front | Why is there is no pus formation in Leukocyte Adhesion Defect (LAD)? |
|---|---|
| Back | Leukocyte Adhesion Defect Type I (LAD I) → CD18 deficiency (LFA-1 integrin) → presents with neutrophils that cannot enter tissue infection site → no pus formation as pus is basically dead neutrophils → neutrophils stay in blood and kill blood-borne infx but the risk of soft tissue infections increases → no bacteremia |
Tags: microbiology
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