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S.Pyogenes Cell Destruction C.Perfringens Major Degradative Toxins C

Front C.perfringens vs. S.pyogenes

Major degradative toxins
Back

C. perfringens 
Lecithinase (aka phospholipase C)
Degrades lecithin in cell membrane → cell membrane destruction → hemolysis → RBC/WBC/Platelet destruction → cell death → necrosis


vs.

S.pyogenes
Hyaluronidase 
Cleaves hyaluronic acid in subcutaneous tissue → acts as a spreading factor for cellulitis

Tags: microbiology

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