ETEC causes traveler's diarrhea through LT toxin, which activates Gs to increase cAMP, and ST toxin, which increases cGMP.
ETEC causes traveler's diarrhea via LT toxin (similar to V. cholera toxin, activating Gs to increase cAMP) and ST toxin (increasing cGMP, similar to Y. enterocolitica toxin).
| Front | ETEC → Traveller's diarrhea → (2) toxins |
|---|---|
| Back | LT Toxin → ADP ribosylation of Gs → ↑AC → ↑cAMP → similar to V.cholera toxin ST Toxin → ↑cGMP similar to Y.enterocolitica toxin |
Learn with these flashcards. Click next, previous, or up to navigate to more flashcards for this subject.
Next card: Dactinomycin adverse effects myelosuppression intercalates dna
Previous card: Pertussis treatment macrolide →
Up to card list: Microbiology 101 → Step 1 USMLE