Apedia

Vaccine Virulence Factors Mechanism Treatment Gi Vi Fever

This card describes Salmonella as a Gram-negative, motile, H2S-producing bacterium transmitted via poultry and undercooked meat. Virulence factors include endotoxin and the Vi capsule. It causes Typhoid Fever, characterized by fever, rose spots, constipation, and abdominal pain. Treatment involves ceftriaxone or fluoroquinolones, and vaccines are available.

Salmonella es una bacteria Gram-negativa que produce H2S y es móvil. Se transmite a través de aves de corral y carne poco cocida. Sus factores de virulencia incluyen endotoxina y la cápsula Vi. Salmonelosis puede causar fiebre tifoidea, que presenta fiebre, manchas rosas, estreñimiento y dolor abdominal. El tratamiento con ceftriaxona o fluoroquinolona es efectivo, y existe una vacuna oral (cepa viva atenuada) o IM (polisacárido capsular Vi).

Front Salmonella

Main features 
Sources
Virulence Factors
Mechanism
Manifestations
Treatment
Vaccine
Back

Gram (-) rods
Oxidase (-) 
Lactose (-)
Flagellar organism which swims
H2S production

Sources: 
Poultry 
Uncooked meat
 ↓


Mechanism
 ↓
Invade GI tract via M cells of Peyer patches




Virulence Factors
 ↓ 
Endotoxin | Vi capsule

Manifestations:
Typhoid Fever → Fever | Rose spots on abdomen | Constipation | Abdominal pain | GI ulceration | Hemorrhage)



Treatment
Ceftriaxone | Fluoroquinolone 

Vaccine
 ↓
Oral vaccine 
(Live attenuated S.typhi)


IM vaccine contains Vi capsular polysaccharide

Tags: microbiology

Learn with these flashcards. Click next, previous, or up to navigate to more flashcards for this subject.

Next card: Symptoms salmonella infection fever headache nausea vomiting rose

Previous card: Salmonella shigella invade gi tract cells m peyer's

Up to card list: Microbiology 101 → Step 1 USMLE