Nocardia is weakly Gram (+), catalase (+), partially acid-fast, with branching filaments that act like fungi. Its virulence factors include cord factor, catalase, and SOD. Manifestations include pulmonary infections and brain abscesses in immunocompromised patients, and diffuse pneumonia; it can spread to the CNS.
Nocardia es débilmente Gram (+), catalasa (+), parcialmente ácido-resistente, con filamentos ramificados que actúan como hongos. Sus factores de virulencia incluyen el factor cordio, la catalasa y la SOD. Las manifestaciones son infecciones pulmonares y abscesos cerebrales en inmunocomprometidos, y neumonía difusa; puede diseminarse al SNC.
| Front | Nocardia Features Virulence Factors Manifestations |
|---|---|
| Back | Weakly Gram (+) Catalase (+) Partially acid fast Branching filaments (act like fungi but are rod-shaped bacteria) Virulence Factors ↓ Cord Factor Catalase SOD Manifestations ↓ Pulmonary infx | Brain abscesses (immunocompromised patients) Diffuse Pneumonia (cough | dyspnea | fever) Similar to TB but with (-) PPD **Spreads to CNS** |
Tags: microbiology
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