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Acetylcholine Role Acetylcholinesterase Stimulus Describe Explain Recycled Recycling

Acetylcholinesterase recycles acetylcholine by hydrolyzing it into choline and ethanoic acid, which are reabsorbed by the presynaptic knob. This prevents continuous receptor stimulation, allowing the synapse to respond to new stimuli and preventing the response from repeating.

La acetilcolinesterasa recicla la acetilcolina hidrolizándola en colina y ácido etanoico, los cuales son reabsorbidos por el botón presináptico. Esto previene la estimulación continua del receptor, permitiendo que la sinapsis responda a nuevos estímulos y evitando la repetición de la respuesta.

Front Describe the role of acetylcholinesterase & explain how acetylcholine is recycled.
Back Acetylcholinesterase:
  • Role in recycling acetylcholine and preventing the response from happening again
  • When neurotransmitter has triggered AP it is important that acetylcholine is hydrolysed so the stimulus is not maintained & another stimulus can arrive and affect synapse
  • Acetylcholinesterase hydrolyses any acetylcholine that is bound to receptors on postsynaptic membrane or leftover in synaptic cleft
  • The products (choline and ethanoic acid) are taken back into presynaptic knob where they are recombined into acetylcholine using ATP


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