A-Level Biology OCR A
Camp Lac Binding Transcription Glucose Rate Crp Lactose
| Front |
Describe the role of cAMP in the control of the lac operon. |
| Back |
Cyclic AMP & lac operon:- Binding of RNA polymerase results in slow rate of transcription that needs to be higher to produce enough enzymes to metabolise lactose
- Binding of cAMP to CRP allows CRP to bind to binding site on promoter & increase rate of transcription of lac operon proteins
- Glucose entering E.coli decreases cAMP - transcription of genes for metabolism of lactose reduced
- If both glucose and lactose present, glucose still preferred
Low glucose:
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High glucose:
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A-Level Biology OCR A