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Collecting Urine Duct Water Concentration Concentrated Tissue Fluid

Front Describe the role of the collecting duct and explain how it can perform this role.
Back Collecting duct:
  • It is the main site where conc and volume of urine is determined
  • Water moves out by diffusion down concentration gradient as it passes thru concentrated tissue fluid of renal medulla
  • Urine becomes more concentrated as result
  • Level of sodium ions in tissue fluid increases through medulla from cortex to pelvis - water can be removed all the way along its length
  • Permeability of collecting duct is controlled by ADH - urine concentration adjustable

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