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A-Level Biology OCR A

Fibers Chromosomes Nuclear Spindle Draw Annotate Describe Occurs

Prophase involves chromatin condensation into chromosomes, disappearance of the nucleolus, spindle fiber formation, and chromosome migration to the center.

During prophase, chromatin condenses into visible chromosomes, the nucleolus disappears, spindle fibers form, and chromosomes move towards the cell's center.

Front Draw, annotate and describe what occurs during prophase.
Back Prophase:
  • Chromatin fibers begin to coil & condense forming chromosomes (visible if stained)
  • Nucleolus disappears, nuclear membrane starts breaking down
  • Protein microtubules form spindle fibers
  • If cell has centrioles, they migrate to opposite poles of cells
  • Spindle fibers attach to specific areas on centromeres, start moving chromosomes to center
  • By the end, nuclear envelope has disappeard

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