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A-Level Biology OCR A

Inactive Enzyme Prevent Precursor Proteases Digesting Vesicles Define

Inactive precursor enzymes are produced to prevent self-damage within cells or to regulate activation under specific conditions.

Inactive precursor enzymes (zymogens) are produced to prevent self-damage within the producing cell or to control enzyme activation under specific conditions.

Front Define inactive precursor enzyme and explain why enzymes may be produced in this form.
Back Inactive precursor enzyme - enzyme that requires biochemical change for it to become active
  • Used to prevent some enzymes from causing damage within cells producing them/tissues where realeased
  • Used when an enzyme's action needs to be controlled and only activated under certain conditions
Example:
  • Used to prevent proteases from digesting membrane proteins in vesicles storing them which would result in vesicles breaking down, prevent proteases from digesting other enzymes
  • Trypsinogen and pepsinogen are inactive forms of trypsin and pepsin, used this way

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