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A-Level Biology OCR A

Substrate Induced Fit Enzyme Describe Hypothesis Shape Slightly Enters

Front Describe the induced-fit hypothesis.
Back Induced-fit hypothesis:
  • Enzyme changes shape slightly as the substrate enters
  • Weak intereactions between substrate and enzyme induce changes in enzyme's tertiary structure that strengthen binding putting strain on substrate molecule
  • This weakens bonds in the substrate, lowering the activation energy

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