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A-Level Biology OCR A

T Cell Helper Pathogen Process Mediated Antigens Form

Front Describe the process of cell mediated immunity.
Back Cell mediated immunity:
  • In non-specific defence macrophages phagocytosed pathogens, process their antigens and form antigen-presenting cells
  • T helper cell with complementary surface receptors to non-self antigens binds to APC
  • T helper cell is stimulated to divide by mitosis to form many clones that differentiate into:
    • T killer cells - destroy pathogen using perforins and toxins that trigger apoptosis
    • T helper cells - secrete interleukins to stimulate phagocytosis and B cell division
    • T memory cells - immunological memory of pathogen
    • T regulator cells - suppress immune respomnse when pathogen removed

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