Phototransduction involves activated rhodopsin activating transducin and phosphodiesterase (PDE), which hydrolyzes cGMP, closing ion channels and hyperpolarizing the photoreceptor membrane.
La phototransduction implique l'activation de la transducine et de la phosphodiestérase (PDE) par la rhodopsine activée, qui hydrolyse le cGMP, fermant les canaux ioniques et hyperpolarisant la membrane du photorécepteur.
| Front | Explain phototransduction |
|---|---|
| Back | 1. light-activated rhodopsin (or photopsin) activates a G protein called transducin 2. Transducin activates phosphodiesterase (PDE) 3. PDE hydrolyzes cGMP to GMP and releases it from Na channels 4. w/o bound cGMP, ion channels close; the membrane hyperpolarizes to ~-70 mV 5. Prevents photoreceptors from releasing inhibitory NT on bipolar cells |
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