Lipid-soluble hormones diffuse across the cell membrane, bind to cytosol or nuclear receptors forming a hormone-receptor complex that binds to DNA, triggering mRNA transcription and protein synthesis.
Οι λιπόφιλες ορμόνες διαπερνούν τη μεμβράνη, συνδέονται με κυτταροπλασματικούς ή πυρηνικούς υποδοχείς, δημιουργώντας ένα σύμπλεγμα ορμόνης-υποδοχέα που είναι δέσμιο στο DNA, προκαλώντας μεταγραφή mRNA και σύνθεση πρωτεΐνης.
| Front | How do lipid-soluble hormones act on target cells? |
|---|---|
| Back | 1. Unbound lipid-soluble hormones diffuse across the cell membrane 2. Hormone binds to a receptor that is located in the cytosol or nucleus to form a hormone-receptor complex 3. Hormone receptor complex binds to DNA sequence on a chromosome (hormone-response element) 4. Triggers transcription of mRNA and subsequent synthesis of a protein |
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