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Plasma Water Soluble Hormones Act Target Cells?  Cross Membrane) 

Water-soluble hormones, unable to cross the plasma membrane, bind to receptors on the cell membrane surface, activating a second messenger signal transduction pathway.

Οι υδατοδιαλυτές ορμόνες, αδυνατώντας να διαπεράσουν τη μεμβράνη, συνδέονται με υποδοχείς στην επιφάνεια της κυτταρικής μεμβράνης, ενεργοποιώντας μια οδός μεταγωγής σήματος δεύτερου αγγελιοφόρου.

Front How do water-soluble hormones act on target cells? 
Back (can't cross the plasma membrane) 
1. Bind to receptors located on the plasma membrane
2. Binding triggers a second messenger signal transduction pathway

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