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Alveoli Air Surface Area Volume Emphysema Affect Lungs

Front How does emphysema affect the lungs
Back Foreign particles trapped in alveoli
Inflammation attracts phagocytes, phagocytes produce an enzyme to break elastin as an immune response.
Alveoli cant recoil to expel air
Destruction of alveoli walls occurs reducing the surface area of alveoli so the rate of diffusion of gases decreases.
Tidal volume reduced, less air is inhaled and exhaled.
Residual volume larger
More difficult to exhale.
Alveoli cannot stretch
Alveoli may burst
Less surface area
Less carbon dioxide removed therefore haemoglobin is less well oxygenated

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