When blood glucose falls, the pancreas detects this, alpha cells release glucagon, and beta cells stop insulin release. Glucagon then stimulates the liver to break down glycogen (glycogenolysis) and synthesize glucose (gluconeogenesis), increasing blood glucose levels.
This card outlines the negative feedback mechanism for a fall in blood glucose: the pancreas detects low levels, alpha cells secrete glucagon, beta cells stop secreting insulin, glucagon acts on the liver to activate glycogenolysis and gluconeogenesis, raising blood glucose.
| Front | Negative feedback mechanism for when there is a fall in blood glucose concentration |
|---|---|
| Back | Pancreas detects blood glucose concentration is too low Alpha cells secrete glucagon Beta cells stop secreting insulin glucagon secreted directly into blood glucagon binds to receptors on liver cells glycogenolysis activation gluconeogenesis activation |
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