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Blood Cells Glucagon Glucose Concentration Activation Negative Feedback

When blood glucose falls, the pancreas detects this, alpha cells release glucagon, and beta cells stop insulin release. Glucagon then stimulates the liver to break down glycogen (glycogenolysis) and synthesize glucose (gluconeogenesis), increasing blood glucose levels.

This card outlines the negative feedback mechanism for a fall in blood glucose: the pancreas detects low levels, alpha cells secrete glucagon, beta cells stop secreting insulin, glucagon acts on the liver to activate glycogenolysis and gluconeogenesis, raising blood glucose.

Front Negative feedback mechanism for when there is a fall in blood glucose concentration
Back Pancreas detects blood glucose concentration is too low

Alpha cells secrete glucagon

Beta cells stop secreting insulin

glucagon secreted directly into blood

glucagon binds to receptors on liver cells

glycogenolysis activation

gluconeogenesis activation

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