Deacetylation increases the positive charge on histones, strengthening their attraction to DNA's phosphate groups, which makes DNA less accessible to transcription factors and switches genes off.
Deacetylation increases the positive charge on histones, strengthening their attraction to DNA's phosphate groups, which makes DNA less accessible to transcription factors and switches genes off.
| Front | What does Deacetylation do the DNA |
|---|---|
| Back | Deacetylation increases positive charge on histones This increases attraction to phosphate groups of DNA Association between DNA and histones stronger DNA not accesible to transcriptional factors Gene switched off |
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