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Immunity Immune System Pathogen Vaccine Varieties Vaccinations Eliminate

Vaccinations might be ineffective if individuals have compromised immune systems, if pathogens undergo frequent mutations altering antigens, if immunity is short-lived, or if multiple pathogen strains exist.

Vaccinations may fail due to defective immune systems, pathogen mutation (antigenic variation), short-lived immunity, or the existence of pathogen varieties for which vaccines are not developed.

Front Why might vaccinations not eliminate a disease
Back The vaccination fails to provide immunity as the person might have a defective immune system
The pathogen may mutate too frequently, antigen change so the vaccine becomes ineffective.
This is called antigenic variation. The immunity is short lived.
There may be varieties of the pathogen which is impossible to develop a vaccine for all the varieties
Certain pathogens may hide from the immune system

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