Methylation of tumor suppressor genes prevents their transcription and subsequent protein production, leading to uncontrolled cell division (mitosis) and potentially cancer.
Leg uit hoe de methylering van tumorsuppressorgenen tot kanker kan leiden. [3 punten]
| Front | Explain how the methylation of tumour suppressor genes can lead to cancer. [3 marks] |
|---|---|
| Back | 1. Methylation prevents transcription of gene; 2. Protein not produced that prevents cell division/ causes cell death/apoptosis; 3. No control of mitosis; |
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