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Substrate Competitive Non Competitive Inhibitors Similar Bind Effect Reversed

Front State three differences between competitive and non-competitive inhibitors ( 3 marks)
Back competitive inhibitors (CIs) structurally similar to substrate
non-competitive inhibitors(NCIs) not similar

CIs bind to active site, NCIs bind elsewhere on enzyme;

effect of NCI is permanent/cannot be reversed by increasing substrate concentration whereas Cl effect is temporary/can be reversed by high substrate concentration;

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